After a lot of difficulty with this,I found the beat way was just to target Zagon.
With a bit of luck,you can pin him up against a wall where he can't move,kill him then high-tail it out of Dodge.
This worked for me after I failed a couple of times. Wasting time trying to deal with the other nuisances just tended to result in premature death. By which I mean mine, not theirs, which wasn't so cunning.
