Don't keep any ok equipment thinking it may be good once you have better charms or enchantments available. By that time you will have found, or will be able to buy, better equipment with just as many charm or enchantment slots.
If you have any creature parts you only need to keep the best of each type. I kept a list of my current top part stats handy so I could sell any lesser versions before talking to the necromancer, so I wouldn't clutter up the part list.
You can also get rid of potion and enchantment formula by talking to the alchemist and enchanter (any left in your inventory after going into the alchemy or enchantment functions will be duplicates, and can be sold).
There is a skill to boost inventory space, if you have the points to spare. You can unlearn all your skills after getting the battle tower, and get those points back once you have access to the chest there to store things.
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