I have exactly the same problem. I have the three ingredients and the correct rune and the teacher says I'm still lacking some ingredients. Leaving the room, dropping everything an taking only the requiered items doesn't help.
So does reinstalling the game.
I guess it means that's the end of Beyond Divinity for me...
EDIT : I just discovered why it happened. It's because of a well known bug in Act 3. I already had a "Wisdom rune" in my inventory. It's not the one I need and it should have disappeared at the end of Act 3. But because of that, I couldn't take the new "Wisdom rune" and I can't go back to where I take it anymore. Anyway, I kept a savegame at the beginning of Act 4. This is all so very tedious but at least I will be able to finish the game eventually.
Last edited by Kyp; 04/09/11 03:34 PM.