You're making it sound like it's already decided Div3 is going to be an 'improved version' of The Dragon Knight Saga, while we already know very well Larian has never produced the same game twice before (ok BD was quite similar to DD, but there were enough differences, including the main character).
Not that I'd regret having the Dragon Slayer again, but having it completely the other way around of the 'to be expected' gameplay might do even better. Thus there are 3 questions we should ask ourselves:
1) Should div3 be a DKS or DOS kind of game? Alternatives? Hybrids?
2) Who should be the hero(ine)? If a new character would be introduced, it might be more fun if this was to be an anti-hero? Besides, we haven't heard much from the non-human races in DKS. No offense, but I believe there's a certain degree of racism within Larian Studios

3) What time setting will it be? Starting the game just after the moment of Igerna's death or several years, decades later? In case of a new hero(ine) it could even start a while BEFORE the ending of DKS and catch not too late.
Here is one last idea. Who said anything about taking down Damian? There's a reason there are story writers at work in game studio's: we don't always want to see what was obvious happen. Remember the ending of Ego Draconis (wich was kind of funny to me, as I imagined the other player's reactions)