Welcome to the forum.

In D2:ED I learned the skill to increase the inventory capacity, and a couple other things I reset once I was able. In DKS I had a much better idea of what I should keep, but still invested in some skills early in the game which were mostly superseded by more effective skills later, so reset for that character, as well (even though I didn't actually need to get back those skill points, with some in reserve for most of the game). I probably will not reset skills with my next character.