NWN 1 used both a grid and weight limitations, which I liked. Even if you can lift 400 pounds, are you going to be able to get your arms around 400 lbs worth of swords and shields? Probably not. Also, the grid system makes moving things around in your inventory far easier (NWN2 made every object the same size, to eliminate the tetris effect). Games like skyrim become frustrating, especially when you're carrying around 300 or so ingredients that you now need to drop into a bin one at a time.

On that note, please oh please don't make the same key for "Take All" work for "Give All". Or at least allow us to change them.