Voice acting uses a lot of space and this game has a LOT of voice acting.
Skyrim and witcher 2 has also a lot of voice acting.
Those were pretty huge games, but despite it's scope I don't think Dragon Commander will be as graphically demanding. Besides the floating Palace/Capital that is the commander's flagship The Raven and the flat battlefields, the game's true depth will lay in strategic implementation of gameplay and story (including voice-acting). Skyrim and Witcher 2 were worlds you could explore - this is a world you need only conquer. That, at least, is what i think.
I've just watched and researched sin of the solar empire/medieval total war II specs. Sin of the solar is roughly 5 gigabytes. While medieval total war II is 9 gigabytes. Latter offers huge map, while the former offers a somewhat similar engine on the RTS system with DC (except they are drawn as a
cartoon icon whenever the player zooms out). I'll assume this are the contents of DC:
5 Gig for graphics (units/battle map/strategy map/inside ship) 2 Gig for gameplay mechanics
1.3 gig for everything else (IE voice acting, dialogues, story scripting)