Especially TB games don´t need very complex controls. This is not Starcraft where you need dozens of shortcuts and macros.
From what I've seen D:OS is more akin to the Infinity Engine games UX-wise (or, obviously, Divine Divinity), porting those to a controller is pretty much not done as they rely very heavily on the mouse for selecting things in the world (unlike, say, Final Fantasy).
The only somewhat successful attempt at a console port of a game in this vein would be Dragon Age: Origins and it was generally agreed that even though the console port didn't suck horribly the PC version was *vastly* superior (iirc they had to cut the pause option from the combat and simplify combat to boot to make the port at all possible).