I'm not getting my hopes up for Div3 to be the one to dwarf them all, nor that such a thing will ever come at all. It's not that I doubt Larian, I certainly believe they have the talent, passion and are on track to do *great things*. It's just that a lot has to go right for that to happen, not to mention needing a significant amount of cash I assume. Here's hoping Original Sin sells like hotcakes ;-)
Though frankly, Original Sin looks pretty freaking great as it is.