From 1.0.45 bugs thread:

*Dialogue bug: In the Fab 5 dialogue, I have to manually switch characters several times to continue
*Also music is acting a bit wonky. In combat I get both the ambient and the combat music playing simultaneously.
*Just had to restart because audio was bugging out completely all of a sudden (after a fight).
*Every pile of gold I pick up is treated as a separate item, I can't combine them.
*Also had the issues with savegames from pre-update being loaded instead of post-update save.
Overwriting seems to have fixed it.