The gaming industry (big publishers) like to claim billions lost due to piracy (after all management is perfect and the only reason their strategy is failing is due to piracy ). The titan quest folks claim the reason their game did so poorly is their anti-piracy code cause the game to crash if it was 'stolen' and so people started writing reviews that the game constantly crashed (legit purchases did not crash).
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I have no clue what the truth is with regards to piracy. At the end of the day piracy only hurts if it results in lost sales (but lets not ignore the damage done by some of these 'drm' systems.
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I personally don't pirate but I known people who think it is 'neat' to 'beat' drm system.
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With regards to D:OS I think it is a potential dis-service to 'pirate' an alpha or early beta because the game is clearly not polished and it might create a false impression of the final product.