Well some Questmarkers like to the Barracks at the beginning or to the mortician would be nice.

But i think what this game really needs is a kind of big tutorial where it shows what you can with the game. Like crafting that you can craft also weopons and not only thingd like french fries or that you can kill a lot of people and still finish the mainquest. You have to show new players that they dont play in a diablo like world but in a world that wants you to have fun and explore things. When i played the game i just did all the quest and killed a lot of enemys first and only later discovered that crafting is really just more than for fun.

I dont know how, but i think this should be done for totally new players that just buy the finished game on steam(or somewhere else) and they dont know anything about the game.