You can hit the Home button to reset the camera angle to default. You should be able to hold the middle button down to rotate the camera clockwise or counterclockwise through a limited range (about 60°)
If you click farther away from the characters they should run. An 'always run' toggle would be nice, though (not to mention a boost to the walk and run speed).
The NPCs should not all be bald.
Did you try changing the resolution or display mode, texture quality, etc, in the graphics options?
Maybe check for updated video drivers.
You can email supportdos@larian.com, with a description of the problem and the report.zip file generated by the
D:OS support tool.
