Did you happen to change the default font size in Windows? I saw in another thread that this caused the buttons to shift downwards. Hitting return should launch the game, as the launch button is selected by default.
This issue is completely unrelated to the game (engine) itself, as this is just a windows form. That being said, some assets and some interface elements/behaviors don't always appear 100% correctly if you deviate from a 16:9 aspect resolution for now. Your resolution however is 16:10, which is pretty close, so I suspect that if something does seem off, it will still be 95% correct.
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