Did you try running a GPU monitoring program to make sure the game is using your GPU and not the integrated graphics? I remember there was a fix in patch 1.0.87.0, "In multi GPU environments, prefer the fastest GPU". Perhaps there are still issues.
To be honest, I didn't know that such programs existed lol Any recommendations?
I have my power management profile set to "high performance", and my Catalyst Control Center has the
Original Sin executable set to "high performance" (i.e. discrete graphics) as well.