Possibly Game Breaking
In the Market near Captain Jack, Roderick spoke to "citizen" who looks similar to Jack. Upon doing so, Roderick froze and fused with citizen. I could open inventory, skills menu, but nothing would change his frozen state. Madora and Scarlett were able to go on.

I saved and then quit game. When I came back in, it was resolved. Screenshot below of guilty citizen.
http://steamcommunity.com/id/rustbucket/screenshot/3316076411151174271

Unfortunately I don't have one of the fused state.

If you rest, you rust.
https://steamcommunity.com/id/rustbucket