For the loss of control during combat, could that be related to use of the Steam overlay while the chat window was visible? If so, hitting Shift will get control back (outside combat clicking and holding to move will, as well, but in combat you'd use AP for that).
If that isn't the problem, if it happens again, please save the game, and after you exit, email supportdos@larian.com, with a description of the problem and the report.zip file generated by the
D:OS support tool. The report will include your saves, so should help Larian figure out what the problem is.
The 2 unique orc armour pieces also have that issue this build.