It shouldnt be done in a hand holding manner, thats for sure.
I think its most important to make sure the players understand the necessity of reading crafting recipes. And to somehow make sure they understand that different items are crafted by different means and ways.
Thats what confusing the most. It certainly confused me.
Because usually in most RPGs (all that i ever played) - you have a specific menu for crafting, into which you put ingredients and then click a button to make an item.
Here in Original Sin, players will get that there are recipes. But im not sure it is immediately clear that you actually have to read them to figure out the proper procedures for different crafting items.
It may become clear after reading a few of those.
Personally i never had any need to craft anything because the overabundance of items and loot.
So i never bothered reading all the recipes.
And there is no way to intuitively figure out different procedures and combinations for all different items. I think.
So. In order of importance:
1. Read those recipe books!
2. Crafting different items require different combinations and procedures.