I've also noticed strangeness with the RNG apparently not hitting, but after I ran a test on a 70% CTH enemy, 10 times (reloading after each attempt), I did get exactly 7 hits. It may just be confirmation bias, we remember the less than expected result (a miss) and forget the hits.
Try with 73% and let me know. It is not a confirmation bias, of that im sure. Reloading might be affecting the freak occurrence that happens in the normal gameplay. As i said, i doubt its a proper bug. Its just... peculiar.