Search the forum for techniques on defeating Josephine. There are various approaches depending on what character class you are playing. If you attack her right away before she is able to complete the death knight summoning it is an easy fight. She will keep trying to re-summon every time she is interrupted, and never get to Blind or Hellspikes. Scorpions or Curse a couple times then Freeze / Elemental Strike, etc. or Blind / Hellspikes can be effective.
