Just writing to share that this was solved!
Looking at the "technical issues" thread by Larian QA, I saw the below:
Problem 4:Strange graphical artifacts in game and very low fps
SolutionGo to your driver settings (nvidia or AMD) and reset 3d application settings to default. Forcing Anti-aliasing via drivers causes several graphics issues.
This did the trick.

Main menu is fine, and wowza--the End of Time location is beautiful!! Thanks!