Right now my favourite start is the following:
Player 1 - Ranger.
Attributes: Dex 8 Speed 7
Skills: Marksman/Scoundrel, Leadership, Loremaster, Lockpicking.
Talents: Leech/Arrow Recovery
Powers: Ranged Power Stance/Tactical Retreat/Walk in Shadows
Player 2 - Knight.
Attributes: Str 7 Int 8
Skills: Aero/Hydro/Pyro/Arms, Tele
Talents: Thick Skin/Pet Pal
Powers: Minor Heal/Flare/Teleportation
By level 3 I pick up Backstabber and Crafting (for making special arrows) on player 1 while player 2 gets Leech. Skillbooks to find in town are Battering Ram for player 2, and razor's edge for player 1 as definites to really help make this group shine.