My strategy:
Focus on Primary stat (the one affecting your skills). Ensure enough to equip gear.
Gear selection also helps offset some "weaker" spots in your point distribution.
Example
9 base Str +1 from items
2 pieced of equipment require 10 str
replace item with +1 str, now 2 items cannot be worn.
I like to avoid situations like the above, as a marked upgrade could potentially not be equipped without sufficient primary stat investment.