The main problems for me is the repetition in conjunction with the overlapping.
Voices repeating over and over is bad enough, but when they start playing over the top of each other in busy areas, it just becomes a cacophony of noise.
I'd read about this issue before booting it up today, and wondered before hand how bad it'd be. Bad enough to stop me from playing and to find out what's happening about it.

Hopefully it's just a bug, and they've already fixed it.
But I'd like it so that the audio is only triggered once when you are pretty close to the NPCs.
For it to be based on line of sight.
And for there to be a good couple of minutes between the loops.