See if there is a '..\Divine Divinity\Run\error.txt' text file with possible errors encountered during install.
Did you try re-installing the game? Zip or otherwise backup your saved games folder (if you got that far) to another location first, just in case. Then un-install, re-boot, shut down all non-essential programs (especially anti-virus), re-install the game, perhaps start the game and see if the problem persists (usually not necessary, but would help identify problems cause by the patch), re-boot, shut down all non-essential programs, install the patch, re-boot, shut down all non-essential programs, start the game. This procedure is a bit over-cautious, but the best way to avoid install problems.