... Are you playing via Steam? If so, then verify your local game cache - maybe some files weren't properly downloaded...
tryed the verification, it foud 5 files not ok, it downloaded them again (88kbyte) and nothing changed

maybe larian have still some optimization to do in the pipeline (someone somewere in the forum mentioned that there are still debug feature active) but i fear it's systemic.
but my best hope resides in a rethinking of how the save process work, eliminating the need of liberating the ram of the cyseal data and then reload them again every time i do a quicksave, but i have no idea of how or why it happen so no idea if it's avoidable.