I've had a few instances where I click through an enemy. It's usually when they do a sudden animation as I click 'em. Hilariously, one enemy with the Weak status seemed like he actively ducked my curses when I went to click. Metagamin' punk enemy!
But really, if you're having issues targeting enemies, I suggest slowing down and watching their movements to avoid it. Best solution, though, is to just hit B and flip to the top-down camera with highlighting. Way easier to target and stuff.
