Wait, no. As long as the mod doesn't introduce new items to the savegame (with a UUID that can only be found in the mod's folder), you CAN add / remove dependencies at will.
All you have to do is overwrite the YourGameName.lsb file in the Savegames/YourGameName folder with a clean one.
This is the case with the mod of this thread. I just tested it and it worked perfectly fine.
What exactly do you mean by a 'clean' one? I've tried removing the mod info in the MyGameName.lsb file via lstools which leads to an incompatible save file.
Edit: Actually, any observations I make right now are probably inaccurate due to me having the fake-Cyseal level from earlier.
