Please email supportdos@larian.com, with a description of the problem and the report.zip file generated by the
D:OS support tool (for the PC version). The report will contain system and game information, any crash dumps, and your saved games. If file size is an issue, most of your saves can be deleted from the zip, since it doesn't seem like they are relevant.
Are you shutting down all non-essential programs (especially anti-virus) before starting the game?
Is your video card overclocked? At least one person reported that caused stability problems. Another reported (
here) that Ambient Occlusion caused their crashes.