Thanks for the report, I'll forward this to design. Your items naturally should not disappear if you have destroyed the chest.

As for you, Calvin, have you tried the loot all button? It may be that your items are still in there, just not visible by the confined container UI (we are aware of this).

If you still do not have your items back, could you send us a report.zip from our support tool? It will allow us to check your D:OS logs and figure out what went wrong.
It can be found here: http://www.larian.com/OriginalSinAlpha/AnalysisTool_DOS.exe
Simply run the tool and click generate report, then send this to supportdos@larian.com with a small description.

Thank you