Hi,
Are you using 32-bit OS system? Could you send us a report.zip from our support tool? It can be found here:
http://www.larian.com/OriginalSinAlpha/AnalysisTool_DOS.exeSimply run the tool and click generate report, then send this to supportdos@larian.com with a small description.
We are aware of memory issues on 32-bit systems and are constantly looking to improve on them. Please try lowering the graphics settings and shut down any non-essential programs running in the background.