I was hit by this as described in wine so its (probably) not only a driver issue.
Anyway, the symptoms are > on load (load takes FOREVER) frame rate unplayable and unplayable for all saves you subconseqently do unless you revert to a older save game without the problem and revert back to the problem save game.
Even then the problem doesnt go away completely, for instance, enabling stealth mode afterwards makes it go back to single digit again (the grayscale shader invalidating a texture cache but still checking?).
A very strange cache is misbehaving here.
Game actually runs pretty good on minimal settings on this prehistoric portable (2009) here without this problem, i was surprised.
Last edited by i30817; 18/07/14 12:10 AM.
