I wouldn't call it losing upwards of 10 skills, most can just be bought again, and by the point you unlock moloch you will be swimming in gold
Only the rare/one-of skills are the actual collateral, or lowlevel skills that no longer appear on vendors.
So what would you call losing upwards of 10 skills, because that is literally what happens.

I have arrow spray. I don't believe I can get that back if I lose it. That seems incredibly unfair, particularly as you aren't warned that it will irreversibly be lost you select that option.
Agree you can buy back most of your skills, but why should I need to? If I have the knowledge, and know I'm going to lose it, then narratively I'm very likely to want to write it down. Just put the spell books for the skills I'm losing in my inventory so I can learn them again if required.