So you don't get to the main menu?
There is a replacement D:OS My Documents folder you could try in the topic
Crash on startup [Solved]. That may help if the problem is in creating the new profile, rather than loading the main menu.
If you have a 32 bit version of Windows, see some suggestions in the topic:
save still causing crash after latest patch.
Most of Larian was on vacation for two weeks, until yesterday, so support has been a little slow.
