I have to experience with left-handed mouse controls but can't you use a mouse that switches the buttons in their hardware?
For example this
one.
Yes I could get a left handed mouse, but why should I have to? Windows provides an option in its control pannel that lets us switch the roles of the mouse buttons. All non game software and a large number of games respect these settings. I currently have a Razer Abyssus mouse I quite like, why should I have to spend alot of money on a left handed mouse because game developers dont respect the way we have our mouse setting configured.
The idea for a mod is more a statement, that if it was possible and lots of people were using it then just maybe the developers may take notice and actualy either make the game respect the windows setting, or a dragon age: origins did, put a check box option in the game to switch to left handed. RPGs like DOS where we are interating with the UI alot are very frustraiting to use this way.
(sorry for using frustrating yet again)