Absolutely.
The only way you can make a single character RPG turn-based would be in the style of NetHack or Castle of the Winds or any of the others (too numerous to mention). In these games, everything is turn based. Every move you make (ie. Walk, fight, open a door, pick something up, etc.) takes time measaured in seconds (or milliseconds). Any creature (ruinning by the same rules as you) whose next turn lies between your, takes it as they see fit. This works surprisingly well. You have some time to think about what you are doing and still have access to all of your skills and spells. And movement speed still means something because it takes different creatures different time to move one square. You can outrun slow powerful creatures, but those bloody wolves will catch you no matter what.
