All Skilled Up, Scientist: Sucks because you can get 10 ability points for this same Talent point by trading it to a demon. Scientist at best breaks even if this is used to get Blacksmithing and Crafting up to 5.
Anaconda, Bigger and Better: You can trade 1 Talent point this for 10 ability points, and then trade those for 2 stat points that should provide a bigger boost than +10 percent damage.
But only the main characters can make a deal with the demon.
Pack Mule: Pretty worthless thanks to multiple party members and a send-to-home button.
I would pick this talent on a single character if I had a party without a STR-based character. I don't know in a party with 2 non-STR lone wolves. It's a matter of inventory management and I hate going to homestead to access the chests. I only send ores to homestead.
118)Companions should not have the Politician talent in their list
It should not be available for Companions, as it offers them no benefit, because they cannot talk to most people.
Charisma gives a bonus to attitude, so it gives a minor benefit while batering with companions. Not that valuable, but I think it justifies the talent being available to companions.
126) More sinew sources needed
Also apparently Sinews, the ONLY way to upgrade bows can only be obtained if you massacre all deer, cows, and sheep in the world, because that is the only way they drop. Or hope you get lucky searching every NPCs ingredient menu.
I would like if bowstrings become available in vendors and as loot.