It wasn't a guaranteed fix, but a couple people during the beta ran into this problem and got their character to be able to talk again by talking to objects; IIRC this helped one person directly, the other it allowed them to talk to rats (or something), and after that they could talk to other animals, and doing that allowed them to talk to NPCs (or maybe just some NPCs first).
For Wolfram, another dialog should have started as you approached, and he would then head to the bar in the King Crab.
Please email supportdos@larian.com, with a description of the problem (or link to this topic) and the report.zip file generated by the
D:OS Analysis Tool (for the PC version). The report will contain system and game information, as well as your saved games. To reduce the file size, you can delete most of the saves from the zip; leave your latest, and (if available) maybe the most recent Madora could speak, and oldest she couldn't.
For Mac, to get system specs you can use the 'System Report' button from the 'About This Mac' Apple menu item or the 'System Information' app (in the utilities folder).
Saves can be zipped by right clicking the folder(s) and selecting Compress, in the folder:
~/Documents/Larian Studios/Divinity Original Sin/PlayerProfiles/<ProfileName>/Savegames
