Love isometric for tactical combat. Over the shoulder for planning out a sequence of turns is not workable, although if someone is masochistic enough to play this way - just unlock the camera.
DOS is easily the best RPG engine available, even though I loved Pillars and am looking forward to Torment, their implementation of the Unity engine just does not offer the powerful mechanics that DOS does.
Would love to have zoomed-in view and an active camera for dialogue / arguments etc.
Active camera = camera that pans between characters. Also - characters will need to gesticulate.
This would however rely on all dialogue lines being voiced.