My computer completely locks up when I start DO:I EE. I had this issue the first day it was released but ran the compatibility troubleshooter and it ran fine. I received an update for the game sometime today and now I've got the problem and can't get rid of it even after running the compatibility trouble shooter.
windows 10 insider preview build 10565 - I think that may be the issue but I'm not sure. Seems like this is the only game I have that issue with.
EDIT - So I uninstalled Cromodo internet security and it appears to have fixed the issue. I was having a bit of a security paranoia issue for a while there (I'm relatively safe with my stuff) but tried it out anyways.