I'll also agree that Div.2 is a rather unique game and stands rather alone; probably the most similar to it in terms of overall "feel" is Oblivion, since they use basically the same engine. Although Oblivion gets a lot of flak, once it's had a few mods thrown at it, it can be transformed into an actually very good game.
In terms of humour, perhaps trickier. Though the gameplay is different, I'd probably suggest Dragon Age Inquisition, which is frequently really quite absurd, whether the random dialogue or some of the curious things that are waiting to be found (I have a soft spot for any game that has a random cheese obsession). And The Witcher 3, though it seems you've already played that.
