There is a limit on the number of items that the game can handle (64k with the patch), though it would take a great deal of crafting and trading to reach (one person did so on PC, at almost 350 hours in the game). However, that would be a consistent crash, if this were the cause.
Please email supportdos@larian.com, with a brief description and a save before one of the traders that is likely to crash. For the benefit of anyone one else with this problem finding this topic, the save would need to be transferred to a USB flash drive first.
In the Saved Data in System Storage section of the Settings menu, click Copy to USB Storage Device, select the relevant save and Copy. From there you can zip the files, then copy to email or upload to Dropbox or Google drive, etc, and provide a link.
