I would love to be able to easily modify the crafting in this game, I think a lot of things could be improved -- not for balancing, but just to enhance it. Here's some of my ideas:

Folded Shirts + Needle = Cloth Scraps
Vial + Vial = Vial Rack
Vial Rack + Potion = Potion Level Up
Any Basket + Any Knife = Rope
Globe + Lab Junk = Sextant

Some other items like Inert Stone and Tube aren't used for anything at the moment either. Also, Tusk + Pixie Dust makes a Magic Tooth instead of a Magic Tusk (but it still uses the icon of a Magic Tusk). Pixie Dust + Chicken Foot as well doesn't correctly say Magic Chicken Foot.

There are two Empty Bottle items that can't be used for anything -- they should be added to the list of items that combined with a Hammer yield a Broken Bottle.

It'd be really awesome if they added this functionality to the editor to allow me to easily make such adjustments instead of having to extract PAK files and edit ItemCombos files, especially since the changes I want to make, a lot of them, involve items that I would have to manually look up.