I watched people not even try out the most simple things because they were convinced before even trying that it would not work. ('Need "Crossbow" ability to use a crossbow', nonsense.)
So while some texts - and dialog organization - could (and should) be improved, the most required device would be a brain washer that washes experience from other games from players' brains, because that is in very many cases the single biggest obstacle. (Also keeps people from trying out things, even if it would be only a single mouse click. Reading seems to be the most unpopular thing in games, that includes even tooltips in the character sheet.)
Who knows, that a PDF game manual exists, at least on Steam ?
Laziness (reading), impatience (Original Sin really requires learning how riddles and quests are done) and most of all 'bad education' by other games are what make Original Sin sometimes seem harder than it really is.
 
You're lamenting "bad education" from other games ruining the experience, but at the same time, D:OS doesn't have much in the way of hand-holding. You know how practically every FPS basically has a tutorial on how to 
just look around?
It's kind of silly to lament the "bad education" from other RPGs while also relying on that education.