Combining all my feedback so far:

Hovering over things. The Swish-ish sound is super annoying.
It seems a minor nitpick, and I dislike starting my feedback with something like this - but wow it gets majorly annoying after only a few minutes hovering over things - the sound seems to pop up on just about every single thing clickable when in character/inventory,etc.

It's something I barely notice usually - so maybe the sound itself has some frequency that gets immediately fatiguing.

Regardless, you could completely remove the sound and it would add immersion and remove distraction.

Needs zoomed out more overall.
Zoomed out all the way is still extremely cramped, especially in combat.

Low Lighting Quality looks better than High.
I see far more 'contrast' with low lighting quality.

Unfortunately I had to stop playing didn't want to continue. I found the zoom level and constant swish sound to be unbearable after about 30 minutes.

Played 250+ hours in D:OS never had an issue - some things so far are way too fatiguing.