I would endorse changing it so that you cannot save the game while in combat.
Honestly, who gives a fluff? If someone wants to save, let them fluffing save. It's not affecting your game. No need to ruin the experience for others.
Eventually, after release, someone is inevitably going to save during a fight they can't win (either intentionally or accidentally) and not be able to get out of that situation and they will have to start their playthrough over from the beginning in order to progress. At that point they will no doubt come to these forums to express their frustration and outrage, saying things like "DIDN'T ANYONE TEST THIS?! WTF??"
and you know what? I'm going to point them to your above quoted post. This, dear frustrated user, is why you have to throw away 10-12 hours of your game and do everything over from the beginning - because we didn't want to "ruin the experience for others"...
