Ya know, you could just really lower the chance of grenade CC working or remove the ones like Charm (which don't rightly make sense anyway).

I loved having grenades in EE though. Hell, I'm recently doing a slow play-through where my entire sheild+one handed fighters thing is to throw grenades around herself while eventually having 100+% all resist from rubies + 15-20% all resist from armor + 15% water resist from eating Clam guy + 25% all resist from absorb elements + 15% all resist from Iron Hide + 40% all resist from Elemental Tortoise.....It's frickin hilarious how she can drop grenades off all types on herself, heal, and avoid CCing herself with bodybuilding and willpower.

Grenades present their own kind of playstyle smile

Making them more rare and expensive and requiring higher crafting would help mitigate abusing them in all builds and playthroughs though.