For D&D the strength and its weakness is the class system, attributes are second class citizens; in order to cover multiple play styles multiclassing was the solution and then attribute considerations came next.
Skills aren't that good of an example to bring up because of the bad exchange rate between attributes and skills (again depending on what edition you're in) and the quantity of ranks per level. Also, the relationship between skills + attributes vs levels is kind of inverted. So, the overall effect of attributes on skills is fairly small depending on which stage of the game - I do not think this is what you want. I
In DSO2, abilities are first class citizen as they have the largest impact in the game and they are what defines your play style based on what you pick. If that's the case then it makes more sense to achieve diversity of builds through abilities rather than attributes keeping it as internally consistent while minimizing side effects.
