There's the Blind Bug where if you get blinded in a fight, even after the fight ends, the reduced accuracy effect stays until you reload the game making it so that you misses almost everytime. I always reload now if the enemy throw the blind dust even once (like the Griff fight) and the fight ends.

But one thing I notice as well though is that some enemies tend to dodge on the first hit even if I reload twice or so. Like, the 3 skeleton in the swamp that talks to you, they always dodge my first arrow.