So I just finished the first act with a solo inquisitor.
There were a couple of hard places - the ambush after the pigs I had to reload the fight 5 or 6 times. The necro Witch was also very hard.
I had to cheat once (by using a bow and the piercing skill) to kill the dragon as I think you can't do it otherwise as his armor regenerates too fast.
I started with Lizard for the extra 2 points on INT then split points pretty much evenly between INT and memory. I ended up (with +3 from elixir and various items) with 26 on each.
The last fight I walked through the front, was not blinded (immunity) and then jumped out of the way and sulked in a corner until everyone had killed everyone else. It then took one shocking touch to kill the worm who was the only one still alive. A bit too easy that.